Zinosine is a high-potency, stable, Zinc Carnosine gastroprotective chelate with proven efficacy for gastric discomfort relief and tissue protection. It works well on its own or as a support to non-steroidal anti-inflammatory treatments and / or traditional gastric support. Zinc Carnosine prevents damage caused by gastric acid, smoke, trauma and most Helicobacter pylori’s gastritis symptoms like nausea, vomiting, heartburn, bloating and burping.
Slow dissociation at target site due to its Chelated Structure
Adheres Firmly and binds to ulcer site and releases Zinc and Carnosine.
Maintains Tissue-Supportive Effects for a long period of time
Promotes gastric epithelial wound repair and accelerates healing of ulcers.
Zinc Carnosine is well tolerated and no zinc accumulation is noted following repeated administration.
Studies have demonstrated that Zinc Carnosine reduces the symptoms associated with acid peptic disorders like heartburn, belching, nausea/vomiting, abdominal distension etc.
A double blind study evaluated the efficacy of Zinc Carnosine in acute and chronic gastritis on 173 subjects. Symptoms, such as epigastrium pain, bloody stools, heartburn, nausea, and vomiting, improved with Zinc Carnosine usage. No serious side effects were reported. Safety percentage came out to be 96.6% and 98.7% in 75 mg & 150 mg dose respectively.
Jpn Pharm Ther 1997;25(5):1403-42
In a double‐blind, randomised, crossover, placebo controlled trial, 5 days of treatment with indomethacin caused a threefold rise in gut permeability. In contrast, when participants received Zinc Carnosine , this prevented the rise in gut permeability caused by indomethacin, strongly suggesting a gastrointestinal protective effect.
Gut. 2007 Feb;56(2):168-175.
In a study, 44 patients with gastric ulcers were given 75 mg of Zinc Carnosine twice daily (after breakfast and before bed). Overall, patients demonstrated favourable improvements in both objective and subjective symptoms: 75.7% at 4 weeks and 89.3% at 8 weeks.No significant side effects were reported.
Jpn Pharm Ther 1992;20(1):1-18
Zinc Carnosine has been clinically demonstrated to be an effective adjunct to proton pump inhibitors and antibiotic therapy in H. pylori eradication.
When combined with a 7-day triple therapy containing lansoprazole, amoxicillin, and clarithromycin, Zinc Carnosine significantly improved the eradication rate of H. pylori infection over triple therapy alone (from 90% to 100%) without increase in side effects.
Aliment PharmacolTher 1999;13:483-87.
In a non-randomized controlled trial , 14 patients with stage II–IV pressure ulcers received 150 mg/day of zinc carnosine for a maximum of 8 weeks. There was significant improvement in the pressure sore healing after 4 weeks and eleven patients healed within 8 weeks.
Biol Trace Elem Res. 2014 Jun;158(3):280-8.
In a study investigating the effect of Zinc L-Carnosine on radiochemotherapy-induced oral mucositis, pain, xerostomia and taste disturbance in patients with head and neck cancer, it was observed that the incidence rates of mucositis, pain, xerostomia and taste disturbance were all markedly lower in Zinc Carnosine group.
Int J Cancer. 2010 Oct 15;127(8):1984-90.
Adults: Zinosine tablet – 1 tablet 2 times a day.
Zinosine Suspension – 1 tsf 3 times per day
Take a few hours before or after taking other medications. Zinosine is taken with or without food, but it is better to take it at a fixed time. It should be taken in the dose and duration as advised by your doctor. Do not exceed more than 2 tablets or 3 tsf a day as it may have harmful effects on your health. Zinc Carnosine is well tolerated and safe to use with minimal common side effects.
Zinosine contains Zinc Carnosine which is a specific chelate of zinc that has been studied in over 100 scientific studies, including at least 45 clinical trials, for its role in supporting stomach health. Research suggests it helps modulate the growth of Helicobacter pylori and promotes healing of the stomach lining.
People suffering from acid peptic disorders like gastritis, ulcers and on NSAIDs would benefit from Zinosine usage . Someone undergoing radiation and chemotherapy which is likely to cause mouth ulcers would also benefit. Bed ridden people with bed sores can also benefit from Zinosine intake. Individuals with mild gastric discomforts, such as occasional heartburn, nausea, bloating, and upset stomach may get relief with Zinosine.
In human studies, Zinosine has demonstrated to have an excellent safety profile with minimal side effects. However one should not exceed intake of Zinosine to more than 2 tablets or 3 tsf a day.
Good clinical compliance has been observed at the typical intake of 150 mg/day. Zinosine is well tolerated and there have been no reports of serious side effects with Zinc Carnosine usage.
Actually, Zinc Carnosine has been scientifically shown to enhance the benefits of antibiotic therapy in H. pylori eradication.