Zinosine Tablets

Zinc Carnosine 75 mg Tablets

Zinosine is a high-potency, stable, Zinc Carnosine gastroprotective chelate with proven efficacy for gastric discomfort relief and tissue protection.It works well on its own or as a support to non-steroidal, anti-inflammatory treatments and/or traditional gastric support.Zinc Carnosine prevents damage caused by gastric acid, smoke, trauma and most helicobacter pylori’s gastritis symptoms like nausea, vomiting, heartburn, bloating and burping.

Why Zinosine?
  • Unique Anti-Ulcer Property
  • Cytoprotective and Tissue Repairing Action
  • Decreases Gut Inflammation
  • Strengthens The Stomach Mucosa
  • Help Maintain the Integrity of the Protective Gastric Mucosal Lining by Supporting Healthy Mucus Secretion
  • Provides Antioxidant Protection for Gastric Mucosal Cells
  • Prevents Radiation-Related Mucositis
  • Inhibits Helicobacter Pylori
Clinical Applications
  • Gastric ulcers
  • Stomatitis
  • NSAIDs induced enteritis
  • Decubitus ulcers / pressure sores
  • Radiation induced stomatitis
  • H pylori infection
  • Ulcerative colitis
  • Gastric health support in Gut damage
Zinosine - Mode of Action
Target Site

Slow dissociation at target site due to its Chelated Structure


Adheres Firmly and blinds to ulcer site and releases Zinc and Carnosine.

Sustained Action

Maintains Tissue-Supportive Effects For A long period of time


Promotes gastric epithelial wound repair and accelerates healing of ulcers.

Zinc Carnosine is well tolerated and no zinc accumulation is noted following repeated administration.

Clinical Efficacy Of Zinc Carnosine

Studies have demonstrated that Zinc Carnosine reduces the symptoms associated with acid peptic disorders like heartburn, belching, nausea/vomiting, abdominal distension etc.

Zinc Carnosine in Gastritis1

A double blind study evaluated the efficacy of Zinc Carnosine in acute and chronic gastritis on 173 subjects. Symptoms, such as epigastrium pain, bloody stools, heartburn, nausea, and vomiting, improved with Zinc Carnosine usage. No serious side effects were reported. Safety percentage came out to be 96.6% and 98.7% in 75 mg & 150 mg dose respectively.

Jpn Pharm Ther 1997;25(5):1403-42

Protective effect of Zinc Carnosine along with Nsaids

In a double‐blind, randomised, crossover, placebo controlled trial, 5 days of treatment with indomethacin caused a threefold rise in gut permeability. In contrast, when participants received Zinc Carnosine , this prevented the rise in gut permeability caused by indomethacin, strongly suggesting a gastrointestinal protective effect.

Gut. 2007 Feb;56(2):168-175.

Zinc Carnosine In Gastric Ulcers

In a study, 44 patients with gastric ulcers were given 75 mg of Zinc Carnosine twice daily (after breakfast and before bed). Overall, patients demonstrated favourable improvements in both objective and subjective symptoms: 75.7% at 4 weeks and 89.3% at 8 weeks.No significant side effects were reported.

Jpn Pharm Ther 1992;20(1):1-18

Zinc Carnosine for Eradication of H Pylori

Zinc Carnosine has been clinically demonstrated to be an effective adjunct to proton pump inhibitors and antibiotic therapy in H. pylori eradication.

When combined with a 7-day triple therapy containing lansoprazole, amoxicillin, and clarithromycin, Zinc Carnosine significantly improved the eradication rate of H. pylori infection over triple therapy alone (from 90% to 100%) without an increase in side effects.

Aliment PharmacolTher 1999;13:483-87.

Zinc Carnosine for pressure sores

In a nonrandomized controlled trial , 14 patients with stage II–IV pressure ulcers received 150 mg/day of zinc carnosine for a maximum of 8 weeks. There was significant improvement in the pressure sore healing after 4 weeks and eleven patients healed within 8 weeks.

Biol Trace Elem Res. 2014 Jun;158(3):280-8.

Zinc Carnosine for Radiation Induced Mucositis

In a study investigating the effect of Zinc L-Carnosine on radiochemotherapy-induced oral mucositis, pain, xerostomia and taste disturbance in patients with head and neck cancer, it was observed that the incidence rates of mucositis, pain, xerostomia and taste disturbance were all markedly lower in Zinc Carnosine group.

Int J Cancer. 2010 Oct 15;127(8):1984-90.

Direction for use

Adults: 1 tablet to be taken 2 times per day.
Take a few hours before or after taking other medications. Zinosinemay is taken with or without food, but it is better to take it at a fixed time. It should be taken in the dose and duration as advised by your doctor. Do not exceed more than 2 tablets a day as it may have harmful effects on your health. Zinc Carnosine is well tolerated and safe to use with minimal common side effects.

What is Zinosine ?

Zinosine contains Zinc Carnosine which is a specific chelate of zinc that has been studied in over 100 scientific studies, including at least 45 clinical trials, for its role in supporting stomach health. Research suggests it helps modulate the growth of Helicobacter pylori and promotes healing of the stomach lining.

Who would benefit from Zinosine?

People suffering from acid peptic disorders like gastritis, ulcers and on NSAIDs would benefit from Zinosine usage . Someone undergoing radiation and chemotherapy which is likely to cause mouth ulcers would also benefit. Bed ridden people with bed sores can also benefit from Zinosine intake. Individuals with mild gastric discomforts, such as occasional heartburn, nausea, bloating, and upset stomach may get relief with Zinosine.

Is it safe?

In human studies, Zinosine has demonstrated to have an excellent safety profile with minimal side effects. However one should not exceed intake of Zinosine to more than 2 tablets a day.

What are the side effects of Zinosine?

Good clinical compliance has been observed at the typical intake of 150 mg/day.Zinosine is well tolerated and there have been no reports of serious side effects with Zinc Carnosine usage.

  • Loss of appetite
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal cramps
  • Headache
  • Zinc Carnosine may also cause side-effects not listed here.
Can Zinosine interact with other medications or supplements?
If you are taking zinc supplements, or any other medications which containing zinc, you need to check with your doctor before taking Zinosine.
Zinc supplementation in high doses may interfere with copper absorption.
Zinc supplements may cause decreased absorption of calcium, in people who do not consume adequate calcium per day 500 mg per day.
Who should take Zinosine with caution?
Due to the lack of human trials, Zinc Carnosine cannot be recommended in children under 12, pregnant women and lactating women. In the elderly, the maximum daily intake should be reduced to less than 100 mg because of reduced digestive functions.
Those with poor livers or with copper-deficiency should not take Zinosine unless supervised by their medical practitioners.
Does it interfere with antibiotic therapy?

Actually, Zinc Carnosine has been scientifically shown to enhance the benefits of antibiotic therapy in H. Pylori eradication.